CAARS 2 Manual Chapter 12: Validity |
The primary intended use of the CAARS 2–ADHD Index is to accurately distinguish between ratings from individuals
with and without ADHD. To validate that the CAARS 2–ADHD Index is effective at this classification activity, scores
on the CAARS 2–ADHD Index were compared between individuals from the general population and individuals with all
presentations of ADHD (i.e., ADHD Inattentive, ADHD Hyperactive/Impulsive, and ADHD Combined). A description of the
Total Sample, which contains the General Population group used here, can be found in Table 6.4 in the
Standardization Phase section of chapter 6,
Development, and details about the ADHD
Reference Samples can be found
in Tables 7.11 to
7.15 of chapter 7,
Standardization.
CAARS 2–ADHD Index probability scores were computed based on raw scores and classified into one of five score
categories, ranging from Very Low to Very High (see Table 4.6 in chapter 4,
Interpretation). The percentage of each
sample with CAARS 2–ADHD Index probability scores in each score category was compared, with results presented in
Table 12.15. Individuals from the General Population group (without a clinical diagnosis)
overwhelmingly received
CAARS 2–ADHD Index probability scores between 1% and 39%, falling in the Very Low and Low ranges (89.2% for
Self-Report; 85.6% for Observer). Conversely, and as expected, individuals diagnosed with ADHD were much more likely
to have CAARS 2–ADHD Index probability scores greater than 59%, falling in the High and Very High ranges (93.7% for
Self-Report, and 81.7% for Observer). Although there is a gradient of possible scores for both groups, it is clear
from the skewed distributions of scores shown in Table 12.15 that the probability score
captures the
increased
likelihood of high scores reflecting ratings from individuals diagnosed with ADHD. These results provide support for
the use of the CAARS 2–ADHD Index for accurate classification of individuals with and without ADHD.
Table 12.15. Distribution of CAARS 2–ADHD Index Probability Scores
Probability Score
|
Self-Report
|
Observer
|
Range
|
Guideline
|
General Population (%)
|
ADHD Reference Sample (%)
|
General Population (%)
|
ADHD Reference Sample (%)
|
1% to 9%
|
Very Low
|
81.2
|
2.4
|
75.5
|
4.7
|
10% to 39%
|
Low
|
8.0
|
3.1
|
10.1
|
5.9
|
40% to 59%
|
Borderline
|
3.3
|
0.8
|
3.7
|
7.6
|
60% to 89%
|
High
|
2.7
|
8.7
|
5.2
|
18.2
|
90% to 99%
|
Very High
|
4.7
|
85.0
|
5.5
|
63.5
|
Note.
Self-Report N = 1,793 for General Population and 255 for ADHD Reference Sample. Observer N = 1,837 for
General
Population and 170 for ADHD Reference Sample.
Another way to examine the ability of the CAARS 2–ADHD Index to predict group membership is to dichotomize scores
into two groups: below 60% (i.e., Very Low, Low, or Borderline ranges, where individuals from the general population
would be expected to score) and 60% or greater (i.e., High or Very High ranges, where individuals diagnosed with
ADHD would be expected to score). Once the data were dichotomized, a second set of analyses investigated the
dichotomized classification category of an obtained probability score in contrast with an individual’s actual group
membership via confusion matrices. Using the approach outlined by Kessel and Zimmerman (1993), the confusion
matrices were then used to derive classification accuracy statistics (see Inconsistency Index in
chapter 6,
Development). Predicting diagnostic status depends on the prevalence of ADHD in the population. The
prevalence (or
base rate of ADHD in the relevant referral population) can vary widely depending on the purpose of the evaluation
and the setting. For example, whereas an ADHD prevalence rate of around 10% or less might be expected in a general
population screening context, expected rates might be around 50% in a clinically referred sample and as high as 80%
among referrals to an ADHD specialty clinic. Accordingly, the classification accuracy statistics, assuming a 50%
base rate, are summarized in Table 12.16, and the Positive Predictive and Negative
Predictive Values
based on
varying base rates are provided in Table 12.17. The overall correct classification rate
was 93.1% for
Self-Report
and 85.5% for Observer.
Table 12.16. Classification Accuracy Statistics: CAARS 2–ADHD Index
Rater
|
Overall Correct Classification Rate (%)
|
Sensitivity (%)
|
Specificity (%)
|
Positive Predictive Value (%)
|
Negative Predictive Value (%)
|
Kappa
|
Self-Report
|
93.1
|
93.7
|
92.5
|
92.6
|
93.6
|
.72
|
Observer
|
85.5
|
81.8
|
89.3
|
88.5
|
83.0
|
.71
|
Table 12.17. Classification Accuracy Statistics Adjusted for Base Rates: CAARS 2–ADHD Index
Rater
|
10% Base Rate
|
60% Base Rate
|
70% Base Rate
|
80% Base Rate
|
PPV (%)
|
NPV (%)
|
PPV (%)
|
NPV (%)
|
PPV (%)
|
NPV (%)
|
PPV (%)
|
NPV (%)
|
Self-Report
|
71.5
|
98.7
|
93.8
|
92.4
|
94.6
|
91.3
|
95.3
|
90.2
|
Observer
|
60.5
|
96.1
|
90.2
|
80.3
|
91.5
|
77.8
|
92.5
|
75.4
|
Note.
PPV = Positive Predictive Value. NPV = Negative Predictive Value.